Lot certificates

You’ll see American Peptides on the lab’s copy. They’re our supplier.

• 5 mg, lot DSIP5-0803: 99.72% purity (RP-HPLC), 5.21 mg measured, identity confirmed by mass spec. Issued 2026-08-28 by Bioviridian Inc.. Verify certificate COA7602

Our vials are filled from lots made by our supplier, American Peptides, and tested by Bioviridian Inc.The laboratory’s original certificate lists American Peptides as the vendor. Look up the code at bioviridians.com to check it.

What researchers study it for

• Sleep and delta-wave EEG activity in animals
• Long-standing insomnia in small human trials
• Circadian timing and hormone levels
• Withdrawal from drugs

How it is thought to work

How DSIP might act is unknown. A 2006 review points out that no gene, precursor protein or receptor for DSIP has ever been found, and describes the idea that it is a sleep factor as weakly supported and poorly documented. The same authors note that certain synthetic analogues promoted sleep in rabbits and rats, while DSIP itself did not.

Where the research stands

Small, older human studies; not an approved medicine. Human research consists of small trials from the 1980s and early 1990s. One double-blind study in 16 people with insomnia saw only weak effects and concluded that a major therapeutic benefit was unlikely. FDA, listing it as emideltide, says it does not have enough safety information.

Sources

1. Schoenenberger GA, Monnier M. (1977). Characterization of a delta-electroencephalogram (-sleep)-inducing peptide. Proceedings of the National Academy of Sciences of the United States of America.
2. Graf MV, Kastin AJ. (1984). Delta-sleep-inducing peptide (DSIP): a review. Neuroscience and Biobehavioral Reviews.
3. Kovalzon VM, Strekalova TV. (2006). Delta sleep-inducing peptide (DSIP): a still unresolved riddle. Journal of Neurochemistry.
4. Bes F, et al. (1992). Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study. Neuropsychobiology.