Lot certificates

You’ll see American Peptides on the lab’s copy. They’re our supplier.

• 10 mg, lot KPV10-0318: 99.73% purity (RP-HPLC), 10.20 mg measured, identity confirmed by mass spec. Issued 2026-08-28 by Bioviridian Inc.. Verify certificate COA7614

Our vials are filled from lots made by our supplier, American Peptides, and tested by Bioviridian Inc.The laboratory’s original certificate lists American Peptides as the vendor. Look up the code at bioviridians.com to check it.

What researchers study it for

• Mouse models of colon inflammation
• Inflammation pathways in gut-lining cells
• Nanoparticle carrier studies
• Short anti-inflammatory peptides from the melanocortin family

How it is thought to work

How it acts is still an open question. In cultured cells, the PepT1 transporter carries KPV into the cell, and lower NF-κB and MAP-kinase activity has been seen alongside that. Work in mice with colitis hints that at least some of what it does happens without the melanocortin-1 receptor.

Where the research stands

Animal and cell studies only. A search of ClinicalTrials.gov turned up no studies in people, and the FDA compounding review says the agency could not find any human exposure information.

Sources

1. Dalmasso G, et al. (2008). PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology.
2. Kannengiesser K, et al. (2008). Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflammatory Bowel Diseases.
3. Luger TA, Brzoska T. (2007). alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Annals of the Rheumatic Diseases.
4. Xiao B, et al. (2017). Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. Molecular Therapy.