Copper & cosmetic
SNAP-8
SNAP-8 is a trade name for acetyl octapeptide-3, sometimes listed as acetyl octapeptide-1, a synthetic peptide of eight amino acids found in cosmetic products. One review gives its sequence as Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp, which includes the six residues of acetyl hexapeptide-3.
- Container
- Glass vial, crimp seal, flip-top cap
- Storage
- 2 to 8 °C, desiccated
- Paperwork
- Lot certificate (HPLC + mass spec) shown before you pay
Lot certificates
You’ll see American Peptides on the lab’s copy. They’re our supplier.
- 10 mg, lot SN810-0803: 99.75% purity (RP-HPLC), 10.47 mg measured, identity confirmed by mass spec. Issued 2026-08-28 by Bioviridian Inc.. Verify certificate COA7620
Our vials are filled from lots made by our supplier, American Peptides, and tested by Bioviridian Inc.The laboratory’s original certificate lists American Peptides as the vendor. Look up the code at bioviridians.com to check it.
What researchers study it for
- Appearance of wrinkles in cosmetic studies
- SNARE complex assembly in the test tube
- Microneedle patch formulations
- Nanoparticle carriers for skin delivery
How it is thought to work
The suggested explanation is that the peptide copies a stretch of the SNAP-25 protein and competes with it when the SNARE complex assembles, which lowers neurotransmitter release in cell experiments. Much of this rests on manufacturer data repeated in review articles. We found no independent confirmation that this happens in skin.
Where the research stands
Cosmetic ingredient; thin independent evidence. Very little peer-reviewed work exists. The two human studies located used microneedle patches containing several ingredients and were written by company-affiliated authors, so nothing can be pinned on this peptide by itself. ClinicalTrials.gov lists no trials.
Sources
- Errante F, et al. (2020). Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy. Frontiers in Chemistry.
- Pintea A, et al. (2025). Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review. Biomolecules.
- Avcil M, et al. (2020). Efficacy of bioactive peptides loaded on hyaluronic acid microneedle patches: A monocentric clinical study. Journal of Cosmetic Dermatology.
- Shin JY, et al. (2024). Clinical Safety and Efficacy Evaluation of a Dissolving Microneedle Patch Having Dual Anti-Wrinkle Effects With Safe and Long-Term Activities. Annals of Dermatology.
For laboratory research use only. Not a drug, food, supplement or cosmetic; not for human or veterinary use. Nothing on this page is medical advice or a usage guide.