Research peptides
L-Glutathione
Glutathione is a three-amino-acid peptide, gamma-L-glutamyl-L-cysteinylglycine, and the most plentiful non-protein thiol in every mammalian tissue. It cycles between a reduced state (GSH) and an oxidized disulfide state (GSSG).
- Container
- Glass vial, crimp seal, flip-top cap
- Storage
- 2 to 8 °C, desiccated
- Paperwork
- Lot certificate (HPLC + mass spec) shown before you pay
Lot certificates
You’ll see American Peptides on the lab’s copy. They’re our supplier.
- 600 mg, lot LGLU600-0528: 99.90% purity (RP-HPLC), 602.43 mg measured, identity confirmed by mass spec. Issued 2026-06-17 by Bioviridian Inc.. Verify certificate COA4841
- 1500 mg, lot GLU1500-0803: 99.76% purity (RP-HPLC), 1505.41 mg measured, identity confirmed by mass spec. Issued 2026-08-28 by Bioviridian Inc.. Verify certificate COA7597
Our vials are filled from lots made by our supplier, American Peptides, and tested by Bioviridian Inc.The laboratory’s original certificate lists American Peptides as the vendor. Look up the code at bioviridians.com to check it.
What researchers study it for
- Oxidative stress and redox signaling
- How cells control glutathione production
- Supplement intake and glutathione levels in the body
- Skin color
- Liver disease and scarring
How it is thought to work
The basic chemistry is well mapped. Cells build glutathione in the cytosol through two enzyme steps; glutamate cysteine ligase sets the pace, and the supply of cysteine matters a great deal. Its antioxidant role runs mostly through glutathione peroxidase, which converts GSH to GSSG; the cell then regenerates GSH using NADPH.
Where the research stands
Human trials exist with mixed results. One randomized study followed 54 adults for half a year and measured a rise in circulating glutathione among those taking the supplement. When systematic reviews pooled research on skin lightening, they judged the overall picture inconclusive and noted that study quality varied. Glutathione is widely available as a dietary supplement.
Sources
- Lu SC. (2013). Glutathione synthesis. Biochimica et Biophysica Acta.
- Richie JP Jr, et al. (2015). Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European Journal of Nutrition.
- Dilokthornsakul W, et al. (2019). The clinical effect of glutathione on skin color and other related skin conditions: A systematic review. Journal of Cosmetic Dermatology.
- Sarkar R, et al. (2025). Glutathione as a skin-lightening agent and in melasma: a systematic review. International Journal of Dermatology.
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For laboratory research use only. Not a drug, food, supplement or cosmetic; not for human or veterinary use. Nothing on this page is medical advice or a usage guide.